Global Technical Development (PTD) is an organization of over two thousand people globally that are integral for the mission of Roche to develop meaningful medicines for patients. Therefore, PTD actively collaborates and develops innovative technical solutions to bridge early-stage, late-stage and commercial product needs. The mandate of the group is to reliably deliver the pipeline and supply quality products to patients. The group excels in its work through innovation, collaboration, dedication, and mutual respect and adds value every day, continuously improving what it does. In Process Chemistry & Catalysis (PTDC-C), we design and develop robust and cost-effective Drug Substance processes using state of the art science and methodologies and the external workbench to deliver the synthetic molecules portfolio from entry into human through transfer to commercial manufacturing, including optimal support for regulatory submissions. Description of the Task: In this role, you will perform end-to-end process chemistry, from the design of new synthetic routes to the development of safe, reliable and sustainable commercial manufacturing processes of synthetic drug substances throughout all clinical phases until transfer to commercial manufacturing. You will either work with our internal process development laboratories or collaborate with our external workbench. You will lead the sourcing of regulatory starting materials, intermediates and services from our external manufacturing network under scientific, technical, environmental and economic considerations. Your Responsibilities: Responsible for the end-to-end development of cost efficient, robust and sustainable processes for our pipeline projects by combining internal and external capabilities by using state of the art science and methodologies to enable lean manufacturing and submissions to health authorities. Authoring of scientific reports, patent applications, and regulatory documents Leading a team of associates in a matrix organization to develop manufacturing processes Working in an interdisciplinary matrix team of Process Chemistry associates, Scientists from analytics and manufacturing, and process engineering experts Managing outsourcing projects on a technical level at external partners. Act as a single point of contact for development and technical aspects at external partners As a chemical project leader, you drive and coordinate all Drug Substance activities within Pharma Technical Development Seek close co-operation with purchasing, SHE-department, quality units and small molecule MSAT group to ensure that projects are run according to Roche guidelines Support of due diligence activities (e.g. on-site visits, CMC assessments, integration planning) Interaction with stakeholders from technical regulatory, quality assurance and formulation development in an international environment Responsible for delivering thorough process understanding by using state of the art science and methodologies to enable lean manufacturing and submissions to health authorities What you bring: PhD in organic chemistry with significant experience (approx. 5 years) in process development of synthetic molecule drug substances. Post-Doc is desirable Excellent understanding of scientific methodology, principles of data integrity and good documentation practices Demonstrated project leadership experience - The ideal candidate seeks to combine strong technical- and managerial skills in this position. Interested to work in cross-functional teams across borders. Familiar with business processes in purchasing and logistics Good overview about regulatory and GMP requirements for development compounds in different clinical phases. Experience in the areas of SHE and Quality-systems is a plus Excellent interpersonal skills to interact with a high number of internal and external stakeholders. Ability to build relationships across departments and functions. Awareness of different cultures and behaviours Excellent communication skills, presents well on complex topics and is able to formulate clear key messages; Experience in writing and reviewing scientific reports and regulatory documents Excellent negotiation skills, fluency in English and German, any other language (e.g. Italian, French, Mandarin) and being familiar with business processes in purchasing and logistics is a plus Ability to work in international/global environment - Willingness to travel (up to 20%) Job Level:Individual contributor This employer is a corporate member of myGwork - LGBTQ+ professionals, the business community for LGBTQ+ professionals, students, inclusive employers & anyone who believes in workplace equality.